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MYZAP Antikörper (C-Term)

MYZAP Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6991501
  • Target Alle MYZAP Antikörper anzeigen
    MYZAP (Myocardial Zonula Adherens Protein (MYZAP))
    Bindungsspezifität
    AA 400-450, C-Term
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 2
    • 1
    Kaninchen
    Klonalität
    • 2
    • 1
    Polyklonal
    Konjugat
    • 3
    Dieser MYZAP Antikörper ist unkonjugiert
    Applikation
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Spezifität
    Multiple isoforms of MYOZAP are known to exist.
    Aufreinigung
    MYOZAP Antibody is affinity chromatography purified via peptide column.
    Immunogen
    MYOZAP antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human MYOZAP. The immunogen is located within amino acids 400 - 450 of MYOZAP.
    Isotyp
    IgG
  • Applikationshinweise
    MYOZAP antibody can be used for detection of MYOZAP by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    MYOZAP Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    MYOZAP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    MYZAP (Myocardial Zonula Adherens Protein (MYZAP))
    Andere Bezeichnung
    MYOZAP (MYZAP Produkte)
    Synonyme
    AA407270 antikoerper, AV006038 antikoerper, Gcom1 antikoerper, Gm640 antikoerper, Grinl1a7 antikoerper, Myozap antikoerper, Myzap antikoerper, GLURR2 antikoerper, GRINL1B antikoerper, GCOM1 antikoerper, Gup antikoerper, Gup1 antikoerper, Gup2 antikoerper, MYOZAP antikoerper, myocardial zonula adherens protein antikoerper, GRINL1B complex locus 2 (pseudogene) antikoerper, Myzap antikoerper, GCOM2 antikoerper, MYZAP antikoerper
    Hintergrund
    MYOZAP Antibody: MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.
    Gen-ID
    100820829
    NCBI Accession
    NP_001018110
    UniProt
    P0CAP1
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