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ZNF219 Antikörper (N-Term)

ZNF219 Reaktivität: Human, Ratte, Maus WB, ELISA, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6991505
  • Target Alle ZNF219 Antikörper anzeigen
    ZNF219 (Zinc Finger Protein 219 (ZNF219))
    Bindungsspezifität
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 90-140, N-Term
    Reaktivität
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 10
    Kaninchen
    Klonalität
    • 10
    Polyklonal
    Konjugat
    • 10
    Dieser ZNF219 Antikörper ist unkonjugiert
    Applikation
    • 10
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Spezifität
    At least two isoforms of ZFP219 are known to exist, this antibody will recognize both.
    Aufreinigung
    ZFP219 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    ZFP219 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human ZFP219. The immunogen is located within amino acids 90 - 140 of ZFP219.
    Isotyp
    IgG
    Top Product
    Discover our top product ZNF219 Primärantikörper
  • Applikationshinweise
    ZFP219 antibody can be used for detection of ZFP219 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    ZFP219 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    ZFP219 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    ZNF219 (Zinc Finger Protein 219 (ZNF219))
    Andere Bezeichnung
    ZFP219 (ZNF219 Produkte)
    Synonyme
    ZNF219 antikoerper, ZFP219 antikoerper, Znf219 antikoerper, 2010302A17Rik antikoerper, zinc finger protein 219 antikoerper, ZNF219 antikoerper, Zfp219 antikoerper
    Hintergrund
    ZFP219 Antibody: ZFP219 is a developmentally regulated member of the Kruppel-like zinc finger gene family that is thought to function as a transcriptional repressor. Yeast two-hybrid screening showed association with Sox9, a transcription factor that is essential for chondrogenesis. ZFP219 is specifically expressed in the developing limb buds and colocalizes with Sox9 in the nucleus. Knockdown of ZFP219 expression decreased Sox9-induced mRNA expression, and a dominant-negative mutant of ZFP219 inhibited Bmp2-induced chondrocyte differentiation, suggesting that ZFP219 plays an important role as a transcriptional partner of Sox9 in the regulation of chondrocyte differentiation.
    Molekulargewicht
    Predicted: 80 kDa

    Observed: 78 kDa
    Gen-ID
    51222
    NCBI Accession
    NP_001095142
    UniProt
    Q9P2Y4
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