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TRMT12 Antikörper (N-Term)

TRMT12 Reaktivität: Human, Maus ELISA, WB, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6991541
  • Target Alle TRMT12 Antikörper anzeigen
    TRMT12 (tRNA Methyltransferase 12 Homolog (TRMT12))
    Bindungsspezifität
    • 2
    • 1
    N-Term
    Reaktivität
    • 11
    • 8
    • 1
    Human, Maus
    Wirt
    • 10
    • 1
    Kaninchen
    Klonalität
    • 11
    Polyklonal
    Konjugat
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TRMT12 Antikörper ist unkonjugiert
    Applikation
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunocytochemistry (ICC)
    Spezifität
    TYW2 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW2 are known to exist, this antibody will detect both isoforms
    Aufreinigung
    TYW2 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    TYW2 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human TYW2. The immunogen is located within the first 50 amino acids of TYW2.
    Isotyp
    IgG
    Top Product
    Discover our top product TRMT12 Primärantikörper
  • Applikationshinweise
    TYW2 antibody can be used for detection of TYW2 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    TYW2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    TYW2 antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    TRMT12 (tRNA Methyltransferase 12 Homolog (TRMT12))
    Andere Bezeichnung
    TYW2 (TRMT12 Produkte)
    Synonyme
    4632406N01Rik antikoerper, AI449275 antikoerper, Tyw2 antikoerper, TRM12 antikoerper, TYW2 antikoerper, RGD1307127 antikoerper, trmt12 antikoerper, tRNA methyltranferase 12 antikoerper, tRNA methyltransferase 12 homolog antikoerper, tRNA methyltransferase 12 antikoerper, tRNA methyltransferase 12 homolog (S. cerevisiae) antikoerper, Trmt12 antikoerper, TRMT12 antikoerper, trmt12 antikoerper
    Hintergrund
    TYW2 Antibody: TYW2, also known as TRM12, is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW2 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation. TYW2 was found to be amplified in 7 of 8 breast cancers cell lines analyzed, and qPCR analysis of 30 breast tumors showed overexpression of TYW2 mRNA of over 2-fold in 26, suggesting that TYW2 may play a role in breast cancer.
    Gen-ID
    55039
    UniProt
    Q53H54
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