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CMYA5 Antikörper (C-Term)

CMYA5 Reaktivität: Human, Maus, Ratte ELISA, WB, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6991554
  • Target Alle CMYA5 Produkte
    CMYA5 (Cardiomyopathy Associated 5 (CMYA5))
    Bindungsspezifität
    AA 3810-3860, C-Term
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 1
    Kaninchen
    Klonalität
    • 1
    Polyklonal
    Konjugat
    • 1
    Dieser CMYA5 Antikörper ist unkonjugiert
    Applikation
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    SPRYD2 antibody is predicted to not cross-react with other SPRYD protein family members. At least four isoforms of SPRYD2 are known to exist.
    Aufreinigung
    SPRYD2 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    SPRYD2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SPRYD2. The immunogen is located within amino acids 3810 - 3860 of SPRYD2.
    Isotyp
    IgG
  • Applikationshinweise
    SPRYD2 antibody can be used for detection of SPRYD2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    SPRYD2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    SPRYD2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    CMYA5 (Cardiomyopathy Associated 5 (CMYA5))
    Andere Bezeichnung
    SPRYD2 (CMYA5 Produkte)
    Synonyme
    cmya5l antikoerper, DKFZp469P2126 antikoerper, C5orf10 antikoerper, SPRYD2 antikoerper, TRIM76 antikoerper, 2310076E16Rik antikoerper, 2310076E21Rik antikoerper, AA420382 antikoerper, AI504003 antikoerper, Srfsd antikoerper, Tims antikoerper, sr553 antikoerper, cardiomyopathy associated 5 antikoerper, CMYA5 antikoerper, cmya5 antikoerper, Cmya5 antikoerper
    Hintergrund
    SPRYD2 Antibody: SPRYD2, also known as Myospryn, was originally identified as the muscle-specific partner of dysbindin and as a Mef-2 target gene. It is a large scaffolding protein localized to the Z-disc/costamere region of striated muscle. SPRYD2 includes a noncanonical tripartite motif (TRIM-like) that lacks the RING domain but consists of a B-box coiled coil (BBC), fibronectin 3 (FN3) repeats, and SPRY domains. SPRYD2 interacts with desmin and calcineurin, and it has been suggested to play a role in the biogenesis of lysosome and negatively regulates slow-fiber-type transformation and skeletal muscle regeneration. SPRYD2 is dysregulated in Duchenne muscular dystrophy.
    Gen-ID
    202333
    NCBI Accession
    NP_705838
    UniProt
    Q8N3K9
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