At least two isoforms of ECRG1 are known to exist, ECRG1 antibody is predicted to not cross-react with other ECRG family members.
Aufreinigung
ECRG1 Antibody is affinity chromatography purified via peptide column.
Immunogen
ECRG1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human ECRG1. The immunogen is located within amino acids 300 - 350 of ECRG1.
TMPRSS11A
Reaktivität: Human
Wirt: Kaninchen
Polyclonal
Biotin
Applikationshinweise
ECRG1 antibody can be used for detection of ECRG1 by Western blot at 1 μ,g/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
ECRG1 Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
ECRG1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ECRG1 Antibody: Epidermal type-II transmembrane serine protease (ECRG1), also known as TMPRSS11A, is a member of a novel esophageal cancer-related gene family. It is a type-II transmembrane serine protease which may play a role in cellular senescence. It is expressed in esophagus, liver, colon and lung. Overexpression of ECRG1 inhibits cell growth and induces G1 cell cycle arrest. It is down-regulated in esophagus cancers (EC) and might play important roles in the initiation and progression of EC.