ANKLE1
(Ankyrin Repeat and LEM Domain Containing 1 (ANKLE1))
Bindungsspezifität
C-Term
Reaktivität
Human, Ratte, Maus
Wirt
Huhn
Klonalität
Polyklonal
Konjugat
Dieser ANKLE1 Antikörper ist unkonjugiert
Applikation
Western Blotting (WB), ELISA
Spezifität
Two isoforms of ANKLE1 are known to exist. ANKLE1 antibody is predicted to not cross-react with ANKLE2
Aufreinigung
ANKLE1 Antibody is affinity chromatography purified via peptide column.
Immunogen
ANKLE1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ANKLE1. The immunogen is located within the last 50 amino acids of ANKLE1.
ANKLE1 antibody can be used for detection of ANKLE1 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
ANKLE1 Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
ANKLE1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
ANKLE1
(Ankyrin Repeat and LEM Domain Containing 1 (ANKLE1))
ANKLE1 Antibody: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. ANKLE1 (Ankyrin repeat and LEM domain containing 1) is a member of ankyrin repeat and LEM domain containing family. It is a potential single-pass membrane protein that contains ankyrin repeats and a Lem domain. Ankyrin repeats mediate protein-protein interactions and are among the most common structural motifs in known proteins. While the function of this protein is still under investigation, its gene locus has been associated with susceptibility to ovarian and breast cancer.