RUSC2 Antikörper (N-Term)

Produktnummer ABIN6991637

Produktdetails anti-RUSC2 Antikörper

Target: RUSC2 (RUN and SH3 Domain Containing 2 (RUSC2))

Bindungsspezifität: AA 70-120, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RUSC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Spezifität: At least three isoforms are known to exist, this antibody will detect all three isoforms. This antibody is predicted to not cross-react with RUSC1.

Aufreinigung: RUSC2 Antibody is affinity chromatography purified via peptide column.

Immunogen: RUSC2 antibody was raised against an 18 amino acid synthetic peptide from near the amino terminus of human RUSC2. The immunogen is located within amino acids 70 - 120 of RUSC2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: RUSC2 antibody can be used for detection of RUSC2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: RUSC2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: RUSC2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu RUSC2

Target: RUSC2 (RUN and SH3 Domain Containing 2 (RUSC2))

Andere Bezeichnung: RUSC2 (RUSC2 Produkte)

Synonyme: MGC142511 antikoerper, DKFZp469H2039 antikoerper, Iporin antikoerper, AI840675 antikoerper, mKIAA0375 antikoerper, RUN and SH3 domain containing 2 antikoerper, RUSC2 antikoerper, rusc2 antikoerper, Rusc2 antikoerper

Hintergrund: RUSC2 Antibody: RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30 % amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.

Gen-ID: 9853

NCBI Accession: NP_055621

UniProt: Q8N2Y8