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PRC1 Antikörper (AA 350-400)

PRC1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6991683
  • Target Alle PRC1 Antikörper anzeigen
    PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))
    Bindungsspezifität
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 350-400
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 22
    • 4
    Kaninchen
    Klonalität
    • 22
    • 4
    Polyklonal
    Konjugat
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PRC1 Antikörper ist unkonjugiert
    Applikation
    • 11
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.
    Aufreinigung
    PRC1 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    PRC1 antibody was raised against a 19 amino acid synthetic peptide near the center of human PRC1. The immunogen is located within amino acids 350 - 400 of PRC1.
    Isotyp
    IgG
    Top Product
    Discover our top product PRC1 Primärantikörper
  • Applikationshinweise
    PRC1 antibody can be used for detection of Prc1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PRC1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    PRC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))
    Andere Bezeichnung
    PRC1 (PRC1 Produkte)
    Synonyme
    cb212 antikoerper, prc1 antikoerper, prc1l antikoerper, zgc:55982 antikoerper, zgc:86918 antikoerper, MGC68845 antikoerper, zgc:55664 antikoerper, ase1 antikoerper, ASE1 antikoerper, D7Ertd348e antikoerper, protein regulator of cytokinesis 1 antikoerper, protein regulator of cytokinesis 1a antikoerper, protein regulator of cytokinesis 1 S homeolog antikoerper, protein regulator of cytokinesis 1b antikoerper, PRC1 antikoerper, prc1a antikoerper, prc1.S antikoerper, prc1b antikoerper, CNC07120 antikoerper, prc1 antikoerper, Prc1 antikoerper
    Hintergrund
    PRC1 Antibody: PRC1 (Protein Regulator of Cytokinesis 1) is a key regulator of cytokinesis and has been identified as a substrate for several cyclin-dependent kinases (CDKs). High levels of PRC1 expression occurs during S and G2/M and drops dramatically after mitosis exit and G1 entry. It is located in the nucleus during interphase and binds to the midzone of mitotic spindles during anaphase and is localized to the cell midbody during cytokinesis. Depletion of PRC1 has been shown to prevent cellular cleavage, but it has no effect on nuclear division, demonstrating the importance of PRC1 in mitosis.
    Gen-ID
    9055
    NCBI Accession
    NP_003972
    UniProt
    O43663
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