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TTYH2 Antikörper (N-Term)

TTYH2 Reaktivität: Human, Maus, Ratte ELISA, WB, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6991699
  • Target Alle TTYH2 Antikörper anzeigen
    TTYH2 (Tweety Homolog 2 (TTYH2))
    Bindungsspezifität
    AA 60-110, N-Term
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 4
    Kaninchen
    Klonalität
    • 4
    Polyklonal
    Konjugat
    • 1
    • 1
    • 1
    • 1
    Dieser TTYH2 Antikörper ist unkonjugiert
    Applikation
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Spezifität
    At least four isoforms of TTYH2 are known to exist, this antibody will only detect the two longest isoforms. This antibody is predicted to not cross-react with other TTYH family members.
    Aufreinigung
    TTYH2 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    TTYH2 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human TTYH2. The immunogen is located within amino acids 60 - 110 of TTYH2.
    Isotyp
    IgG
    Top Product
    Discover our top product TTYH2 Primärantikörper
  • Applikationshinweise
    TTYH2 antibody can be used for detection of TTYH2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    TTYH2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    TTYH2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    TTYH2 (Tweety Homolog 2 (TTYH2))
    Andere Bezeichnung
    TTYH2 (TTYH2 Produkte)
    Synonyme
    RGD1562969 antikoerper, C17orf29 antikoerper, 1110001A03Rik antikoerper, tweety family member 2 antikoerper, tweety family member 2 S homeolog antikoerper, Ttyh2 antikoerper, TTYH2 antikoerper, ttyh2.S antikoerper
    Hintergrund
    TTYH2 Antibody: TTYH2 is a member of the tweety family of proteins, a family of chloride anion channels containing five transmembrane regions. TTYH2 is a Ca2+-activated large conductance chloride (Cl-) channel and may play a role in kidney tumorigenesis. It is also upregulated in colon carcinoma and is thought to play a role in cell proliferation and call aggregation, suggesting that TTYH2 may play a role in regulating both proliferation and metastatic potentials of colorectal cancer. The ubiquitin-protein ligase Nedd4-2 binds to and ubiquitinates TTYH2, thereby regulating its cell surface expression and total cellular levels.
    Gen-ID
    94015
    NCBI Accession
    NP_116035
    UniProt
    Q9BSA4
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