DELE1/KIAA0141 Antikörper (N-Term)

Produktnummer ABIN6991710

Produktdetails anti-DELE1/KIAA0141 Antikörper

Target: DELE1/KIAA0141 (DELE1) (DAP3 Binding Cell Death Enhancer 1 (DELE1))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DELE1/KIAA0141 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Aufreinigung: DELE Antibody is affinity chromatography purified via peptide column.

Immunogen: DELE antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human DELE. The immunogen is located within the first 50 amino acids of DELE.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: DELE antibody can be used for detection of DELE by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: DELE Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: DELE antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu DELE1/KIAA0141

Target: DELE1/KIAA0141 (DELE1) (DAP3 Binding Cell Death Enhancer 1 (DELE1))

Andere Bezeichnung: DELE (DELE1 Produkte)

Synonyme: KIAA0141 antikoerper, MGC139304 antikoerper, DELE antikoerper, 2700004E22Rik antikoerper, Dele antikoerper, Kiaa0141 antikoerper, KIAA0141 antikoerper, KIAA0141 ortholog antikoerper, RIKEN cDNA 0610009O20 gene antikoerper, SEL1 domain containing protein RGD735029 antikoerper, KIAA0141 antikoerper, 0610009O20Rik antikoerper, RGD735029 antikoerper

Hintergrund: DELE Antibody: DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-α, and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-α, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors.

Gen-ID: 9812

NCBI Accession: NP_055588

UniProt: Q14154