ANKRD15 Antikörper (N-Term)

Produktnummer ABIN6991851

Produktdetails anti-ANKRD15 Antikörper

Target: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANKRD15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Two alternatively spliced transcript variants encoding different isoforms have been identified. The lower molecular weight band seen in the immunoblot is thought to be non-specific.

Aufreinigung: KANK1 Antibody is affinity chromatography purified via peptide column.

Immunogen: KANK1 antibody was raised against a 19 amino acid peptide near the amino terminus of human KANK1 . The immunogen is located within the first 50 amino acids of KANK1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: KANK1 Antibody can be used for detection of KANK1 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: KANK1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: KANK1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu ANKRD15

Target: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Andere Bezeichnung: KANK1 (ANKRD15 Produkte)

Synonyme: ANKRD15 antikoerper, CPSQ2 antikoerper, KANK antikoerper, A930031B09Rik antikoerper, AU015049 antikoerper, AW121052 antikoerper, Ankrd15 antikoerper, D330024H06Rik antikoerper, mKIAA0172 antikoerper, KANK1 antikoerper, ankrd15 antikoerper, kank1.2 antikoerper, DMRT1 antikoerper, KN motif and ankyrin repeat domains 1 antikoerper, KN motif and ankyrin repeat domains 1 L homeolog antikoerper, doublesex and mab-3 related transcription factor 1 antikoerper, KANK1 antikoerper, Kank1 antikoerper, kank1.L antikoerper, DMRT1 antikoerper

Hintergrund: KANK1 Antibody: Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK1 (KN motif and ankyrin repeat domain-containing protein 1), also known as ANKRD15, is a 1,352 amino acid protein that contains at least 12 exons and 5 ANK repeats. It binds to beta-catenin and regulates its subcellular distribution. KANK1 is ubiquitously expressed and localizes to cytoplasm. It may function as a tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder.

Molekulargewicht: Predicted: 149 kDa

Observed: 150 kDa

Gen-ID: 23189

NCBI Accession: NP_055973

UniProt: Q14678

Pathways: Regulation of Actin Filament Polymerization