Two alternatively spliced transcript variants encoding different isoforms have been identified.
Aufreinigung
KANK2 Antibody is affinity chromatography purified via peptide column.
Immunogen
KANK2 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human KANK2 . The immunogen is located within the last 50 amino acids of KANK2.
KANK2
Reaktivität: Human
IP
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
KANK2 Antibody can be used for detection of KANK2 by Western blot at 1 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
KANK2 Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
KANK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target
KANK2
(KN Motif and Ankyrin Repeat Domains 2 (KANK2))
KANK2 Antibody: Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK2 (KN motif and ankyrin repeat domain-containing protein 2), was initially identified as a steroid receptor coactivator (SRC) interacting protein (SIP) that could sequester steroid receptor coactivators in the cytoplasm. More recent experiments have shown that while KANK2 is widely expressed, in kidney podocytes, KANK2 localizes to foot processes, suggesting that KANK2 may contribute to controlling actin dynamics in podocyte foot processes.