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DIS3 Antikörper (N-Term)

DIS3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6991861
  • Target Alle DIS3 Antikörper anzeigen
    DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 90-140, N-Term
    Reaktivität
    • 44
    • 15
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 39
    • 5
    Kaninchen
    Klonalität
    • 42
    • 2
    Polyklonal
    Konjugat
    • 24
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DIS3 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 21
    • 15
    • 6
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Spezifität
    Multiple isoforms of DIS3 are known to exist.
    Aufreinigung
    DIS3 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    DIS3 antibody was raised against an 18 amino acid peptide near the amino terminus of human DIS3. The immunogen is located within amino acids 90 - 140 of DIS3.
    Isotyp
    IgG
    Top Product
    Discover our top product DIS3 Primärantikörper
  • Applikationshinweise
    DIS3 antibody can be used for detection of DIS3 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    DIS3 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    DIS3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))
    Andere Bezeichnung
    DIS3 (DIS3 Produkte)
    Synonyme
    EXOSC11 antikoerper, KIAA1008 antikoerper, RP11-342J4.3 antikoerper, RRP44 antikoerper, bA555G22.1 antikoerper, dis3p antikoerper, DIS3 antikoerper, 2810028N01Rik antikoerper, RGD1304646 antikoerper, wu:fb08g12 antikoerper, dis3 antikoerper, DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease antikoerper, DIS3 exosome endoribonuclease and 3'-5' exoribonuclease antikoerper, DIS3 antikoerper, Dis3 antikoerper, dis3 antikoerper, dis3.L antikoerper
    Hintergrund
    DIS3 Antibody: The exosome is involved in a multitude of cellular RNA processing and degradation events. DIS3, also known as exosome complex exonuclease RRP44, is a ribonuclease that acts directly in the processing, turnover, and surveillance of a large number of distinct RNA species. DIS3 localizes to both the cytoplasm and the nucleus and contains one PINc domain. It is widely expressed with highest expression in testis and is required for processing of 7S pre-RNA into a mature nuclear complex and, ultimately, for proper mitotic progression. Abnormal expression levels of DIS3 may be associated with colon cancer, suggesting a role for DIS3 in tumorigenesis.
    Molekulargewicht
    Predicted: 105 kDa

    Observed: 103 kDa
    Gen-ID
    22894
    NCBI Accession
    NP_055768
    UniProt
    Q9Y2L1
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