Kallikrein 4 Antikörper (AA 80-130)

Produktnummer ABIN6991891

Produktdetails anti-Kallikrein 4 Antikörper

Target: Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))

Bindungsspezifität: AA 80-130

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: KLK4 antibody is human specific. At least three isoforms of KLK4 are known to exist.

Aufreinigung: KLK4 Antibody is affinity chromatography purified via peptide column.

Immunogen: KLK4 antibody was raised against a 15 amino acid peptide near the center of human KLK4. The immunogen is located within amino acids 80 - 130 of KLK4 .

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: KLK4 antibody can be used for detection of KLK4 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: KLK4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: KLK4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu Kallikrein 4

Target: Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))

Andere Bezeichnung: KLK4 (KLK4 Produkte)

Synonyme: ESMP1 antikoerper, KLK-L1 antikoerper, PSTS antikoerper, Prss17 antikoerper, AI2A1 antikoerper, ARM1 antikoerper, EMSP antikoerper, EMSP1 antikoerper, PRSS17 antikoerper, kallikrein antikoerper, Emsp1 antikoerper, kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) antikoerper, kallikrein related peptidase 4 antikoerper, kallikrein-related peptidase 4 antikoerper, Klk4 antikoerper, KLK4 antikoerper

Hintergrund: Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes having diverse physiological functions (1). Kallikrein 4 (KLK4), also known as prostase or EMSP1 (enamel matrix serine protease 1), contains one peptidase S1 domain and the expression in prostate is regulated by hormone (1,2). Many kallikreins are implicated in carcinogenesis and have potential as novel cancer and other disease biomarkers (3). KLK4 may have additional roles such as functioning as one of the two major enamel proteases identified that process enamel matrix proteins. Defects in KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) (4).

Molekulargewicht: Predicted: 28 kDa

Observed: 31kDa

Gen-ID: 9622

NCBI Accession: NP_004908

UniProt: Q9Y5K2

Pathways: Komplementsystem