LC3C Antikörper (C-Term)

Produktnummer ABIN6991933

Produktdetails anti-LC3C Antikörper

Target: LC3C (MAP1LC3C) (Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LC3C Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: MAP1LC3C antibody is human, mouse and rat reactive. Multiple isoforms MAP1LC3C are known to exist. MAP1LC3C antibody is predicted to not cross-react with MAP1LC3A or MAP1LC3B.

Aufreinigung: MAP1LC3C antibody is affinity chromatography purified via peptide column.

Immunogen: MAP1LC3C antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MAP1LC3C. The immunogen is located within the last 50 amino acids of MAP1LC3C.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: MAP1LC3C antibody can be used for detection of MAP1LC3C by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: MAP1LC3C antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: MAP1LC3C antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu LC3C

Target: LC3C (MAP1LC3C) (Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C))

Andere Bezeichnung: MAP1LC3C (MAP1LC3C Produkte)

Synonyme: MAP1LC3C antikoerper, MGC154878 antikoerper, ATG8J antikoerper, LC3C antikoerper, microtubule associated protein 1 light chain 3 gamma antikoerper, microtubule associated protein 1 light chain 3 gamma L homeolog antikoerper, MAP1LC3C antikoerper, map1lc3c antikoerper, map1lc3c.L antikoerper

Hintergrund: Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1). MAP1LC3C belongs to the MAP1 LC3 family of proteins that form mature complexes with MAP1A and MAP1B which are thought to be important in the formation and development of axons and dendrites (2). MAP1LC3C is one of three isoforms of MAP1LC3, the mammalian homolog of yeast ATG8, an essential autophagy protein. These isoforms exhibit distinct expression patterns and MAP1LC3C, like MAP1LC3A but not MAP1LC3B, is post-translationally modified, suggesting the three isoforms may have different physiological functions (3).

Molekulargewicht: Predicted: 16 kDa

Observed: 16 kDa

Gen-ID: 440738

NCBI Accession: NP_001004343

UniProt: Q9BXW4

Pathways: Autophagie