TMIGD1 antibody is human, mouse and rat reactive. At least two isoforms of TMIGD1 are known to exist, this antibody will detect both isoforms.
Aufreinigung
TMIGD1 antibody is affinity chromatography purified via peptide column.
Immunogen
TMIGD1 antibody was raised against an 18 amino acid peptide near the center of human TMIGD1. The immunogen is located within amino acids 150 - 200 of TMIGD1.
TMIGD1 antibody can be used for detection of TMIGD1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
TMIGD1 antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
TMIGD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target
TMIGD1
(Transmembrane and Immunoglobulin Domain Containing 1 (TMIGD1))
TMIGD1 (transmembrane and immunoglobulin domain containing 1) is a 262 amino acid single-pass membrane protein that contains two Ig-like C2-type (immunoglobulin-like) domains (1,2). It is a nonsecreted, glycosylated protein located in the cytoplasm and cell membrane (1). TMIGD1 might be a possible cell-differentiation marker in the intestine, whose expression is lost during cellular transformation and promote progression of tumorigenesis in the intestinal epithelium (2-4). TMIGD1 has also been postulated to play a role in cell adhesion (2).