GLIPR1L2 antibody is human specific. At least two isoforms of GLIPR1L2 are known to exist, this antibody will detect both isoforms. This antibody is predicted to not cross-react with other GLIPR or GLIPR-like proteins.
Aufreinigung
GLIPR1L2 antibody is affinity chromatography purified via peptide column.
Immunogen
GLIPR1L2 antibody was raised against an 15 amino acid peptide near the center of human GLIPR1L2. The immunogen is located within amino acids 120 - 170 of GLIPR1L2.
GLIPR1L2
Reaktivität: Human
WB, EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
GLIPR1L2 antibody can be used for detection of GLIPR1L2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
GLIPR1L2 antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
GLIPR1L2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target
GLIPR1L2
(GLI Pathogenesis-Related 1 Like 2 (GLIPR1L2))
4921508O11Rik antikoerper, GLI pathogenesis related 1 like 2 antikoerper, GLI pathogenesis-related 1 like 2 antikoerper, GLIPR1L2 antikoerper, Glipr1l2 antikoerper
Hintergrund
The GLIPR1-like 2 protein (GLIPR1L2) gene is part of a p53 target gene cluster that includes the related proteins GLIPR1 and GLIPR1L2 (2). GLIPR1L2 is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family (1). GLIPR1 is a tumor suppressor whose expression is regulated by p53 (3). Deletions of the GLIPR1/GLIPR1L1/GLIPR1L2 gene cluster have been observed in some multiple myeloma samples, suggesting that these proteins may also be involved in the pathogenesis of multiple myeloma (4).