GDPD5 antibody is human, mouse and rat reactive. At least three isoforms of GDPD5 are known to exist.
Aufreinigung
GDPD5 antibody is affinity chromatography purified via peptide column.
Immunogen
GDPD5 antibody was raised against an 18 amino acid peptide near the amino terminus of human GDPD5. The immunogen is located within the first 50 amino acids of GDPD5.
GDPD5 antibody can be used for detection of GDPD5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
GDPD5 Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
GDPD5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Zhang, Dai, Zhao, Wang, Dou, Zhuang, Chen, Zhao et al.: "MiR-874-3p represses the migration and invasion yet promotes the apoptosis and cisplatin sensitivity via being sponged by long intergenic non-coding RNA 00922 (LINC00922) and targeting ..." in: Bioengineered, Vol. 13, Issue 3, pp. 7082-7104, (2022) (PubMed).
The glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) protein, also known as GDE2, is a seven transmembrane, widely expressed protein (1) that is necessary for spinal motor neuron differentiation and retinoid-induced neuronal outgrowth (2,3). Altered choline phospholipid metabolism is a hallmark of cancer, and the elevated expression of GDPD5 correlates with malignant choline phospholipid metabolite profiles in human breast cancer (4).