Density Regulated Protein Antikörper (AA 80-130)
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- Target Alle Density Regulated Protein (DENR) Antikörper anzeigen
- Density Regulated Protein (DENR) (Density-Regulated Protein (DENR))
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Bindungsspezifität
- AA 80-130
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Density Regulated Protein Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- DENR antibody is human, mouse and rat reactive.
- Aufreinigung
- DENR antibody is affinity chromatography purified via peptide column.
- Immunogen
- DENR antibody was raised against an 18 amino acid peptide near the center of human DENR. The immunogen is located within amino acids 80 - 130 of DENR.
- Isotyp
- IgG
- Top Product
- Discover our top product DENR Primärantikörper
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- Applikationshinweise
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DENR antibody can be used for detection of DENR by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- DENR Antibody is supplied in PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,4 °C
- Informationen zur Lagerung
- DENR antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Target
- Density Regulated Protein (DENR) (Density-Regulated Protein (DENR))
- Andere Bezeichnung
- DEN (DENR Produkte)
- Hintergrund
- DENR (density-regulated protein), also designated DRP or smooth muscle cell associated protein 3 (SMAP-3), is a 198 amino acid protein that may be involved in the translation of target mRNAs by scanning and recognition of the initiation codon (1). It plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1 (2,3). DENR contains a SUI1 domain and is found in a variety of tissues with highest levels present in skeletal and cardiac muscle. It is up-regulated in ovarian and breast cancer cells by ERBB2 overexpression (4).
- Molekulargewicht
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Predicted: 22 kDa
Observed: 22 kDa - Gen-ID
- 8562
- NCBI Accession
- NP_003668
- UniProt
- O43583
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