WAPAL Antikörper (N-Term)

Produktnummer ABIN6992007

Produktdetails anti-WAPAL Antikörper

Target: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Bindungsspezifität: AA 30-80, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WAPAL Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: WAPL antibody is human, mouse and rat reactive. At least four isoforms of WAPL are known to exist.

Aufreinigung: WAPL antibody is affinity chromatography purified via peptide column.

Immunogen: WAPL antibody was raised against an 18 amino acid peptide near the amino terminus of human WAPL. The immunogen is located within amino acids 30 - 80 of WAPL.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WAPL antibody can be used for detection of WAPL by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: WAPL antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: WAPL antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu WAPAL

Target: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Andere Bezeichnung: WAPL (WAPAL Produkte)

Synonyme: RGD1308960 antikoerper, FOE antikoerper, KIAA0261 antikoerper, WAPL antikoerper, 2410073G16 antikoerper, A530089A20Rik antikoerper, BC037674 antikoerper, mKIAA0261 antikoerper, mWAPL antikoerper, WAPL cohesin release factor antikoerper, Wapl antikoerper, WAPL antikoerper, wapl antikoerper

Hintergrund: WAPL (wings apart-like), also known as WAPAL or FOE, is a 1,190 amino acid protein that contains one WAPL domain and may play an important role in cell growth (1). It is expressed in an isoform dependent manner in heart, skeletal muscle (isoform 2) and uterine cervix tumor tissue (isoform 1) (1,2,4). WAPL is involved in sister-chromatid adhesion and promotes release of cohesin from chromosomes by directly interacting with its regulatory subunits (3,4). WAPL is a new regulator of the development and metastasis of cancerous tissue (4,5).

Molekulargewicht: Predicted: 131 kDa

Observed: 140 kDa

Gen-ID: 23063

NCBI Accession: NP_055860

UniProt: Q7Z5K2

Pathways: Chromatin Binding