BAMBI antibody is affinity chromatography purified via peptide column.
Immunogen
BAMBI antibody was raised against a 17 amino acid peptide near the center of human BAMBI. The immunogen is located within amino acids 100 - 150 of BAMBI.
BAMBI
Reaktivität: Human, Ratte, Maus, Schwein
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 594
Applikationshinweise
BAMBI antibody can be used for detection of BAMBI by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
BAMBI antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
BAMBI antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target
BAMBI
(BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))
NMA antikoerper, bambi antikoerper, nma antikoerper, BAMBI antikoerper, Zfnma antikoerper, cb998 antikoerper, fc44c12 antikoerper, id:ibd5020 antikoerper, wu:fc44c12 antikoerper, wu:fe01e03 antikoerper, 2610003H06Rik antikoerper, bambi-A antikoerper, zgc:91871 antikoerper, BMP and activin membrane bound inhibitor antikoerper, BMP and activin membrane-bound inhibitor homolog antikoerper, BMP and activin membrane-bound inhibitor antikoerper, BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a antikoerper, BMP and activin membrane-bound inhibitor L homeolog antikoerper, BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) b antikoerper, BAMBI antikoerper, bambi antikoerper, bambia antikoerper, Bambi antikoerper, LOC724378 antikoerper, LOC100647353 antikoerper, bambi.L antikoerper, bambib antikoerper
Hintergrund
BAMBI (BMP and activin membrane-bound inhibitor homolog, NMA) is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development (1). BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4 (2,3). BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues (4). BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines (5).