VEZT Antikörper (AA 480-530)

Produktnummer ABIN6992059

Produktdetails anti-VEZT Antikörper

Target: VEZT (Vezatin, Adherens Junctions Transmembrane Protein (VEZT))

Bindungsspezifität: AA 480-530

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VEZT Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Spezifität: VEZT antibody is human, mouse and rat reactive. Multiple isoforms are known to exist.

Aufreinigung: VEZT antibody is affinity chromatography purified via peptide column.

Immunogen: VEZT antibody was raised against a 17 amino acid peptide near the center of human VEZT. The immunogen is located within amino acids 480 - 530 of VEZT.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: VEZT antibody can be used for detection of VEZT by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: VEZT antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: VEZT antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu VEZT

Target: VEZT (Vezatin, Adherens Junctions Transmembrane Protein (VEZT))

Andere Bezeichnung: VEZT (VEZT Produkte)

Synonyme: DKFZp469O2222 antikoerper, VEZATIN antikoerper, 6330418D12 antikoerper, AI854408 antikoerper, vezatin antikoerper, vezatin, adherens junctions transmembrane protein antikoerper, vezatin, adherens junctions transmembrane protein L homeolog antikoerper, VEZT antikoerper, vezt antikoerper, Vezt antikoerper, vezt.L antikoerper

Hintergrund: Vezatin (VEZT) is a transmembrane protein which localizes to adherens junctions and binds to myosin VIIA and the cadherin-catenins complex (1). Expression of this gene in gastric cancer tissues is decreased due to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts (2). VEZT has also been shown to be required for morphogenesis of the preimplantation mouse embryo (3).

Molekulargewicht: Predicted: 63, 68, 78, 81, 83, 86 kDa

Observed: 60 kDa

Gen-ID: 55591

NCBI Accession: NP_060069

UniProt: Q9HBM0