Neuroligin 2 Antikörper (C-Term)

Produktnummer ABIN6992063

Produktdetails anti-Neuroligin 2 Antikörper

Target: Neuroligin 2 (NLGN2)

Bindungsspezifität: AA 630-680, C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neuroligin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: NLGN2 antibody is human, mouse and rat reactive. At least two isoforms are known to exist, this antibody will detect both isoforms. NLGN2 antibody is predicted to not cross-react with other members of the NLGN protein family.

Aufreinigung: NLGN2 antibody is affinity chromatography purified via peptide column.

Immunogen: NLGN2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human NLGN2. The immunogen is located within amino acids 630 - 680 of NLGN2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: NLGN2 antibody can be used for detection of NLGN2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: NLGN2 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: NLGN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu Neuroligin 2

Target: Neuroligin 2 (NLGN2)

Andere Bezeichnung: NLGN2 (NLGN2 Produkte)

Synonyme: Nlgn2 antikoerper, GB10066 antikoerper, NLGN2 antikoerper, CCE-L2 antikoerper, NV50031 antikoerper, Nv123771 antikoerper, NL2 antikoerper, RP23-422L16.24 antikoerper, neuroligin 2 antikoerper, LOC410779 antikoerper, NLGN2 antikoerper, LOC663865 antikoerper, LOC100123771 antikoerper, Nlgn2 antikoerper

Hintergrund: Neuroligin 2 (NLGN2) is a member of a family of neuronal cell surface proteins that localize to the post-synaptic membrane (1,2). Neuroligins are thought to act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses (2). NLGN2 has been shown to control perisomatic inhibitory synapse maturation together with gephyrin and collybistin, thereby regulating GABA receptor clustering on neurons (3,4). NLGN2 also exhibits differential functions at different types of inhibitory synapses on the same postsynaptic neuron (5).

Molekulargewicht: Predicted: 92, 99 kDa

Observed: 80, 97 kDa

Gen-ID: 57555

NCBI Accession: NP_065846

UniProt: Q8NFZ4

Pathways: Cell-Cell Junction Organization, Synaptic Membrane