PRRX1 Antikörper (AA 70-120)

Produktnummer ABIN6992105

Produktdetails anti-PRRX1 Antikörper

Target: PRRX1 (Paired Related Homeobox 1 (PRRX1))

Bindungsspezifität: AA 70-120

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRRX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: PRRX1 antibody is human, mouse and rat reactive. At least two isoforms of PRRX1 are known to exist, this antibody will detect both isoforms.

Aufreinigung: PRRX1 antibody is affinity chromatography purified via peptide column.

Immunogen: PRRX1 antibody was raised against a 19 amino acid peptide near the center of human PRRX1. The immunogen is located within amino acids 70 - 120 of PRRX1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PRRX1 antibody can be used for detection of PRRX1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PRRX1 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PRRX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu PRRX1

Target: PRRX1 (Paired Related Homeobox 1 (PRRX1))

Andere Bezeichnung: PRRX1 (PRRX1 Produkte)

Hintergrund: The paired related homeobox protein 1 (PRRX1) is a paired-type DNA-binding homeodomain that plays an important role as a key switch for neural cell lineage determination and is essential for development (1,2). PRRX1 is expressed in a number of undifferentiated mesenchymal cells in mouse embryos and adults (3). Mice with a disrupted PRRX1 gene show perinatal death with craniofacial and limb malformations (4). Low PRRX1 expression levels were significantly associated with metastasis and poor prognosis of breast and colorectal cancer (5).

Molekulargewicht: Predicted: 27 kDa

Observed: 26 kDa

Gen-ID: 5396

NCBI Accession: NP_073207

UniProt: P54821