SLC29A3 antibody is human, mouse and rat reactive. At least two isoforms of SLC29A3 are known to exist, this antibody will detect both isoforms. SLC29A3 antibody is predicted to not cross-react with other SLC29 proteins.
Aufreinigung
SLC29A3 antibody is affinity chromatography purified via peptide column.
Immunogen
SLC29A3 antibody was raised against a 19 amino acid peptide near the amino terminus of human SLC29A3. The immunogen is located within the first 50 amino acids of SLC29A3.
SLC29A3
Reaktivität: Human
WB, ELISA, IHC
Wirt: Kaninchen
Polyclonal
HRP
Applikationshinweise
SLC29A3 antibody can be used for detection of SLC29A3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
SLC29A3 antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
SLC29A3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target
SLC29A3
(Solute Carrier Family 29 Member 3 (SLC29A3))
ENT3 antikoerper, HCLAP antikoerper, HJCD antikoerper, PHID antikoerper, Ent3 antikoerper, 4933435C21Rik antikoerper, AW987637 antikoerper, solute carrier family 29 member 3 antikoerper, solute carrier family 29 (nucleoside transporters), member 3 antikoerper, SLC29A3 antikoerper, Slc29a3 antikoerper
Hintergrund
SLC29A3 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2). SLC29A3 is a transmembrane glycoprotein that localizes to the lysosomal membrane and is a broad selectivity, low affinity nucleoside transporter (3). Mutations in the SLC29A3 gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism (4). A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus (5).