Western Blotting (WB), ELISA, Immunofluorescence (IF)
Spezifität
MKRN3 antibody is human specific. MKRN3 antibody is predicted to not cross-react with other members of the MKRN protein family.
Aufreinigung
MKRN3 antibody is affinity chromatography purified via peptide column.
Immunogen
MKRN3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human MKRN3. The immunogen is located within amino acids 400 - 450 of MKRN3.
CPPB2 antikoerper, D15S9 antikoerper, RNF63 antikoerper, ZFP127 antikoerper, ZNF127 antikoerper, D7H15S9-1 antikoerper, Zfp127 antikoerper, makorin ring finger protein 3 antikoerper, makorin, ring finger protein, 3 antikoerper, MKRN3 antikoerper, Mkrn3 antikoerper
Hintergrund
The Makorin ring finger 3 (MKRN3) protein contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. The MKRN3 gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome (1), but a deletion of the gene does not (2). A deficiency of MKRN3 has been shown to cause central precocious puberty in humans (3).