Relaxin 3 Antikörper (AA 80-130)

Produktnummer ABIN6992136

Produktdetails anti-Relaxin 3 Antikörper

Target: Relaxin 3 (RLN3)

Bindungsspezifität: AA 80-130

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Relaxin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: RLN3 antibody is human specific. RLN3 antibody is predicted to not cross-react with other members of the Relaxin protein family.

Aufreinigung: RLN3 antibody is affinity chromatography purified via peptide column.

Immunogen: RLN3 antibody was raised against a 19 amino acid peptide near the center of human RLN3. The immunogen is located within amino acids 80 - 130 of RLN3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: RLN3 antibody can be used for detection of RLN3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: RLN3 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: RLN3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu Relaxin 3

Target: Relaxin 3 (RLN3)

Andere Bezeichnung: RLN3 (RLN3 Produkte)

Hintergrund: Relaxin-3 (RLN3) is a member of Relaxin family, a group of endocrine and autocrine/paracrine hormones that belong to the insulin gene superfamily (1,2). RLN3 can bind to and activate three relaxin-family peptide receptors: RXFP1, RXFP3, and RXFP4 (3). In contrast to the widespread expression of the related proteins RLN1 and RLN2, RLN3 is predominantly expressed in brain and to a lesser extent in the thymus, kidney and spleen (1). RLN3 has been suggested to play a role in feeding, metabolism, stress, arousal, learning, and memory (4).

Molekulargewicht: Predicted: 16 kDa

Observed: 16 kDa

Gen-ID: 117579

NCBI Accession: NP_543140

UniProt: Q8WFX3

Pathways: Hormone Activity, cAMP Metabolic Process