PACS1 Antikörper (AA 430-480)
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- Target Alle PACS1 Antikörper anzeigen
- PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))
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Bindungsspezifität
- AA 430-480
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PACS1 Antikörper ist unkonjugiert
- Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Spezifität
- PACS1 antibody is human, mouse and rat reactive. Multiple isoforms of PACS1 are known to exist. PACS1 antibody is predicted to not cross-react with PACS2.
- Aufreinigung
- PACS1 antibody is affinity chromatography purified via peptide column.
- Immunogen
- PACS1 antibody was raised against a 17 amino acid peptide near the center of human PACS1. The immunogen is located within amino acids 430 - 480 of PACS1.
- Isotyp
- IgG
- Top Product
- Discover our top product PACS1 Primärantikörper
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- Applikationshinweise
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PACS1 antibody can be used for detection of PACS1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PACS1 antibody is supplied in PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,4 °C
- Informationen zur Lagerung
- PACS1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Target
- PACS1 (phosphofurin Acidic Cluster Sorting Protein 1 (PACS1))
- Andere Bezeichnung
- PACS1 (PACS1 Produkte)
- Synonyme
- MRD17 antikoerper, AI325977 antikoerper, Pacs-1 antikoerper, phosphofurin acidic cluster sorting protein 1 antikoerper, PACS1 antikoerper, Pacs1 antikoerper
- Hintergrund
- The phosphofurin acidic cluster sorting protein 1 (PACS1), belongs to the PACS family of cytosolic connector proteins that localize different membrane proteins to the trans-Golgi network (TGN) (1,2). Mutations in PACS1 cause defects in cranial-neural crest migration during early development, leading to a recognizable intellectual disability syndrome (3). PACS1, along with the related protein PACS2, also plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance (4).
- Molekulargewicht
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Predicted: 106 kDa
Observed: 105 kDa - Gen-ID
- 55690
- NCBI Accession
- NP_060496
- UniProt
- Q6VY07
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