KIR2DS2 Antikörper (C-Term)

Produktnummer ABIN6992145

Produktdetails anti-KIR2DS2 Antikörper

Target: KIR2DS2 (Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIR2DS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: KIR2DS2 antibody is human specific. Multiple isoforms are known to exist.

Aufreinigung: KIR2DS2 antibody is affinity chromatography purified via peptide column.

Immunogen: KIR2DS2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KIR2DS2. The immunogen is located within the last 50 amino acids of KIR2DS2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: KIR2DS2 antibody can be used for detection of KIR2DS2 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: KIR2DS2 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: KIR2DS2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu KIR2DS2

Target: KIR2DS2 (Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))

Andere Bezeichnung: KIR2DS2 (KIR2DS2 Produkte)

Synonyme: 183ActI antikoerper, CD158J antikoerper, CD158b antikoerper, NKAT5 antikoerper, cl-49 antikoerper, killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2 antikoerper, KIR2DS2 antikoerper

Hintergrund: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells (1). The KIR proteins are classified by the number of extracellular immunoglobulin domains and by whether they have a long (L) or short (S) cytoplasmic domain (2,3). KIR proteins are thought to play an important role in regulation of the immune response (3). KIR2DS2 downregulates the cytotoxicity of NK cells upon recognition of specific class I major histocompatibility complex (MHC) molecules on target cells and is a receptor on natural killer (NK) cells for HLA-C alleles (3,4).

Molekulargewicht: Predicted: 28, 33, 37 kDa

Observed: 34, 42 kDa

Gen-ID: 100132285

NCBI Accession: NP_036444

UniProt: P43631