Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
VTI1a antibody is human, mouse and rat reactive. At least two isoforms of VTI1a are known to exist, this antibody will detect both isoforms. VTI1a antibody is predicted to not cross-react with VTI1b.
Aufreinigung
VTI1a antibody is affinity chromatography purified via peptide column.
Immunogen
VTI1a antibody was raised against a 19 amino acid peptide near the center of human VTI1a. The immunogen is located within amino acids 50 - 100 of VTI1a.
VTI1A
Reaktivität: Human
Wirt: Kaninchen
Polyclonal
FITC
Applikationshinweise
VTI1a antibody can be used for detection of VTI1a by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
VTI1a antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
VTI1a antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target
VTI1A
(Vesicle Transport through Interaction with t-SNAREs 1A (VTI1A))
zgc:109895 antikoerper, mvti1 antikoerper, vti1-rp2 antikoerper, DDBDRAFT_0219803 antikoerper, DDBDRAFT_0231536 antikoerper, DDB_0219803 antikoerper, DDB_0231536 antikoerper, MMDS3 antikoerper, MVti1 antikoerper, VTI1RP2 antikoerper, Vti1-rp2 antikoerper, 1110014F16Rik antikoerper, 1110018K19Rik antikoerper, 4921537J05Rik antikoerper, MVti1a antikoerper, Vti1 antikoerper, vesicle transport through interaction with t-SNAREs 1A L homeolog antikoerper, vesicle transport through interaction with t-SNAREs 1A antikoerper, v-SNARE family protein antikoerper, vti1a.L antikoerper, vti1a antikoerper, VTI1A antikoerper, vti1A antikoerper, Vti1a antikoerper
Hintergrund
Vesicle transport through interaction with t-SNAREs homolog 1 (VTI1a and VTI1b) are involved in vesicular transport from the late endosomes to the trans-Golgi network (1). They are both localized in the trans-Golgi network, with VTI1a also found in the Golgi apparatus and VTI1b in endosomes (2,3). VTI1a mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane and promotes fusion of the lipid bilayers (4). VTI1a may be concerned with increased secretion of cytokines associated with cellular senescence (5).