HOOK3 Antikörper (N-Term)

Produktnummer ABIN6992177

Produktdetails anti-HOOK3 Antikörper

Target: HOOK3 (Hook Homolog 3 (HOOK3))

Bindungsspezifität: AA 210-260, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOOK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: HOOK3 antibody is human, mouse and rat reactive. HOOK3 antibody is predicted to not cross-react with HOOK1 and HOOK2.

Aufreinigung: HOOK3 Antibody is affinity chromatography purified via peptide column.

Immunogen: HOOK3 antibody was raised against a 19 amino acid peptide from near the amino terminus of human HOOK3. The immunogen is located within amino acids 210 - 260 of HOOK3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: HOOK3 antibody can be used for the detection of HOOK3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry at 10 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: HOOK3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: HOOK3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu HOOK3

Target: HOOK3 (Hook Homolog 3 (HOOK3))

Andere Bezeichnung: HOOK3 (HOOK3 Produkte)

Synonyme: 5830454D03Rik antikoerper, AI317159 antikoerper, E330005F07Rik antikoerper, HK3 antikoerper, hook3 antikoerper, hook microtubule-tethering protein 3 antikoerper, hook microtubule tethering protein 3 antikoerper, hook microtubule-tethering protein 3 L homeolog antikoerper, Hook3 antikoerper, HOOK3 antikoerper, hook3.L antikoerper

Hintergrund: The HOOK proteins (HOOK1, HOOK2 and HOOK3) comprise a family of cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules mediating the spatial organization of diverse membrane-trafficking systems, their more divergent C-terminal domains mediate binding to organelles (1,2). HOOK3 exists as a homodimer and participates in defining the architecture and localization of the Golgi complex through its central coiled-coil domain (3). HOOK3 may regulate clearance of endocytosed receptors such as MSR1 (3,4).

Molekulargewicht: Predicted: 79 kDa

Observed: 77 kDa

Gen-ID: 84376

NCBI Accession: NP_115786

UniProt: Q86VS8

Pathways: Stem Cell Maintenance, Maintenance of Protein Location