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SARS-CoV-2 ORF7a Antikörper (C-Term)

Reaktivität: SARS Coronavirus-2 (SARS-CoV-2) ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6992305
  • Target Alle SARS-CoV-2 ORF7a Produkte
    SARS-CoV-2 ORF7a
    Bindungsspezifität
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 4
    • 1
    SARS Coronavirus-2 (SARS-CoV-2)
    Wirt
    • 3
    • 1
    • 1
    Kaninchen
    Klonalität
    • 4
    • 1
    Polyklonal
    Konjugat
    • 5
    Dieser SARS-CoV-2 ORF7a Antikörper ist unkonjugiert
    Applikation
    • 4
    • 3
    • 1
    • 1
    • 1
    ELISA
    Aufreinigung
    SARS-CoV-2 (COVID-19) ORF7a Antibody is affinity chromatography purified via peptide column.
    Immunogen
    Anti-SARS-CoV-2 (COVID-19) ORF7a antibody was raised against a peptide corresponding to 9 amino acids near the carboxyl terminus of SARS-CoV-2 (COVID-19) ORF7a protein. The immunogen is located within the last 50 amino acids of the SARS-CoV-2 (COVID-19) ORF7a protein.
    Isotyp
    IgG
  • Applikationshinweise
    Antibody validated: SARS-CoV-2 (COVID-19) ORF7a antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    SARS-CoV-2 (COVID-19) ORF7a antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    SARS-CoV-2 (COVID-19) ORF7a antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    SARS-CoV-2 ORF7a
    Abstract
    SARS-CoV-2 ORF7a Produkte
    Synonyme
    ORF7a protein antikoerper, ORF7a antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund
    Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). SARS-CoV-2 virus proteins include structural proteins, non-structural proteins and accessory factors. The structure of SARS-CoV-2 consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. SARS-CoV-2 non-structural protein is ORF1ab that consists of 16 proteins (nsp1-nsp16), while accessory factors include ORF3a, ORF3b, ORF6, ORF7a, ORF7b, ORF8, ORF9b, ORF7a and ORF7a. ORF7a plays a role as antagonist of host tetherin (BST2), disrupting its antiviral effect. It acts by binding to BST2 thereby interfering with its glycosylation. It may suppress small interfering RNA (siRNA) and may bind to host ITGAL, thereby playing a role in attachment or modulation of leukocytes (3).
    Molekulargewicht
    14kD kDa
    Gen-ID
    43740573
    UniProt
    P0DTC7
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