KNSTRN Antikörper
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- Target Alle KNSTRN Antikörper anzeigen
- KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KNSTRN Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant Human Small kinetochore-associated protein protein
- Isotyp
- IgG
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- Applikationshinweise
- WB 1:500-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 2 mg/mL
- Buffer
- PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))
- Andere Bezeichnung
- C15orf23 (KNSTRN Produkte)
- Synonyme
- 1700025D04Rik antikoerper, C15orf23 antikoerper, D2Ertd750e antikoerper, SKAP antikoerper, Traf4af1 antikoerper, TRAF4AF1 antikoerper, kinetochore-localized astrin/SPAG5 binding antikoerper, kinetochore localized astrin/SPAG5 binding protein antikoerper, kinetochore-localized astrin/SPAG5 binding protein antikoerper, Knstrn antikoerper, KNSTRN antikoerper
- Hintergrund
- Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase . Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division.
- Molekulargewicht
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Observed_MW: 35 kDa
Calculated_MW: 35 kDa
- UniProt
- Q9Y448
- Pathways
- M Phase
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