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KNSTRN Antikörper

KNSTRN Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7233849
  • Target Alle KNSTRN Antikörper anzeigen
    KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))
    Reaktivität
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 5
    Kaninchen
    Klonalität
    • 5
    Polyklonal
    Konjugat
    • 5
    Dieser KNSTRN Antikörper ist unkonjugiert
    Applikation
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant Human Small kinetochore-associated protein protein
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    2 mg/mL
    Buffer
    PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    KNSTRN (Kinetochore-Localized Astrin/SPAG5 Binding Protein (KNSTRN))
    Andere Bezeichnung
    C15orf23 (KNSTRN Produkte)
    Synonyme
    1700025D04Rik antikoerper, C15orf23 antikoerper, D2Ertd750e antikoerper, SKAP antikoerper, Traf4af1 antikoerper, TRAF4AF1 antikoerper, kinetochore-localized astrin/SPAG5 binding antikoerper, kinetochore localized astrin/SPAG5 binding protein antikoerper, kinetochore-localized astrin/SPAG5 binding protein antikoerper, Knstrn antikoerper, KNSTRN antikoerper
    Hintergrund
    Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase . Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. Required for kinetochore oscillations and dynamics of microtubule plus-ends during live cell mitosis, possibly by forming a link between spindle microtubule plus-ends and mitotic chromosomes to achieve faithful cell division.
    Molekulargewicht

    Observed_MW: 35 kDa

    Calculated_MW: 35 kDa

    UniProt
    Q9Y448
    Pathways
    M Phase
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