PCK1 Antikörper
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- Target Alle PCK1 Antikörper anzeigen
- PCK1 (phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1))
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PCK1 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Antigen Affinity Purification
- Immunogen
- Recombinant Rat Phosphoenolpyruvate carboxykinase, cytosolic [GTP] protein
- Isotyp
- IgG
- Top Product
- Discover our top product PCK1 Primärantikörper
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- Applikationshinweise
- IHC 1:100-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PCK1 (phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1))
- Andere Bezeichnung
- PCK1 (PCK1 Produkte)
- Hintergrund
- This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
- UniProt
- P07379
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
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