IL-6 Receptor Antikörper
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- Target Alle IL-6 Receptor (IL6R) Antikörper anzeigen
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
- Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IL-6 Receptor Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Antigen Affinity Purification
- Immunogen
- Recombinant Human Interleukin-6 receptor subunit alpha protein
- Isotyp
- IgG
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anti-Interleukin 6 Receptor (IL6R) (AA 20-320) antibody
IL6R Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 216-356) antibodyIL6R Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) antibodyIL6R Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 1-468) antibodyIL6R Reaktivität: Human WB, FACS Wirt: Maus Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 205-347) antibodyIL6R Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 385-462) antibodyIL6R Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) antibodyIL6R Reaktivität: Human IHC, IP, ELISA, FACS, Func Wirt: Maus Monoclonal B-R6 unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 1-468) antibodyIL6R Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 21-120) antibodyIL6R Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1E11 unconjugated
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- Applikationshinweise
- WB 1:1000-1:2000 IHC 1:100-1:300
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
- Andere Bezeichnung
- IL6R (IL6R Produkte)
- Hintergrund
- This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
- Molekulargewicht
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Observed_MW: 80 kDa
Calculated_MW: 40,51 kDa
- UniProt
- P08887
- Pathways
- JAK-STAT Signalweg, Autophagie, Growth Factor Binding, Cancer Immune Checkpoints
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