PLAUR Antikörper

Produktnummer ABIN7234357

Produktdetails anti-PLAUR Antikörper

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLAUR Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen Affinity Purification

Immunogen: Recombinant Human Urokinase plasminogen activator surface receptor protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.85 mg/mL

Buffer: PBS with 0.05 % Proclin300, 50 % glycerol, pH 7.3

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PLAUR

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Andere Bezeichnung: PLAUR (PLAUR Produkte)

Synonyme: Cd87 antikoerper, u-PAR antikoerper, uPAR antikoerper, CD87 antikoerper, U-PAR antikoerper, UPAR antikoerper, URKR antikoerper, Par antikoerper, Plaur3 antikoerper, uPAR-2 antikoerper, uPAR-3 antikoerper, PLAUR antikoerper, plasminogen activator, urokinase receptor antikoerper, Plaur antikoerper, PLAUR antikoerper

Hintergrund: This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

Gen-ID: 5329

UniProt: Q03405

Pathways: Inositol Metabolic Process