COX4NB antikoerper, NOC4 antikoerper, MGC75783 antikoerper, cox4nb antikoerper, fb54g02 antikoerper, noc4 antikoerper, wu:fb54g02 antikoerper, zgc:56331 antikoerper, C16orf2 antikoerper, C16orf4 antikoerper, FAM158B antikoerper, Cox4nb antikoerper, Fam158b antikoerper, Noc4 antikoerper, ER membrane protein complex subunit 8 antikoerper, ER membrane protein complex subunit 8 S homeolog antikoerper, ER membrane protein complex subunit 9 antikoerper, EMC8 antikoerper, emc8 antikoerper, emc8.S antikoerper, EMC9 antikoerper, Emc8 antikoerper
Hintergrund
COX4NB (Neighbor of COX4) is a 210 amino acid protein encoded by the human gene COX4NB. COX4NB belongs to the UPF0172 (NOC4) family and is found on chromosome 16, adjacent to the gene that encodes COX4. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16 through the CREBBP gene which encodes a critical CREB binding protein. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other auto-immune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.