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CRELD2 Antikörper

CRELD2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7236677
  • Target Alle CRELD2 Antikörper anzeigen
    CRELD2 (Cysteine-Rich with EGF-Like Domains 2 (CRELD2))
    Reaktivität
    • 43
    • 17
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 54
    • 4
    Kaninchen
    Klonalität
    • 57
    • 1
    Polyklonal
    Konjugat
    • 17
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CRELD2 Antikörper ist unkonjugiert
    Applikation
    • 50
    • 30
    • 14
    • 13
    • 13
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human CRELD2
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.3 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CRELD2 (Cysteine-Rich with EGF-Like Domains 2 (CRELD2))
    Andere Bezeichnung
    CRELD2 (CRELD2 Produkte)
    Synonyme
    zgc:66383 antikoerper, CRELD2 antikoerper, 5730592L21Rik antikoerper, C85758 antikoerper, RGD1310614 antikoerper, cysteine-rich with EGF-like domains 2 antikoerper, cysteine rich with EGF like domains 2 antikoerper, creld2 antikoerper, CRELD2 antikoerper, Creld2 antikoerper
    Hintergrund
    The epidermal growth factor (EGF) repeat-containing proteins constitute an expanding family of proteins that are involved in several cellular activities, such as blood coagulation, fibrinolysis, cell adhesion and neural and vertebrate development. CRELD2 (cysteine-rich with EGF-like domains 2) is a 353 amino acid protein that is ubiquitously expressed and contains two FU domains and two EGF-like domains. Localized to the endoplasmic reticulum and secreted into the cell, CRELD2 interacts with AChR4, possibly regulating its transport. Human CRELD2 shares 69 % amino acid identity with its mouse counterpart, suggesting a conserved role between species. Multiple isoforms of CRELD2 exist due to alternative splicing events. The gene encoding CRELD2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
    Molekulargewicht
    38 kDa
    UniProt
    Q6UXH1
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