ALDA antikoerper, GSD12 antikoerper, aldoa antikoerper, cb79 antikoerper, sb:cb79 antikoerper, wu:fa28b10 antikoerper, wu:fb10b11 antikoerper, ALDOA antikoerper, Aldo-1 antikoerper, Aldo1 antikoerper, RNALDOG5 antikoerper, hm:zeh0036 antikoerper, zgc:77696 antikoerper, aldolase, fructose-bisphosphate A antikoerper, aldolase a, fructose-bisphosphate, a antikoerper, aldolase, fructose-bisphosphate A S homeolog antikoerper, aldolase A, fructose-bisphosphate antikoerper, aldolase a, fructose-bisphosphate, b antikoerper, ALDOA antikoerper, aldoaa antikoerper, aldoa antikoerper, aldoa.S antikoerper, Aldoa antikoerper, aldoab antikoerper
Hintergrund
The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.