HYAL3 Antikörper

Produktnummer ABIN7237226

Produktdetails anti-HYAL3 Antikörper

Target: HYAL3 (Hyaluronidase-3 (HYAL3))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HYAL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human HYAL3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu HYAL3

Target: HYAL3 (Hyaluronidase-3 (HYAL3))

Andere Bezeichnung: HYAL3 (HYAL3 Produkte)

Synonyme: HYAL1 antikoerper, HYAL3 antikoerper, Hyal-3 antikoerper, HYAL-3 antikoerper, LUCA-3 antikoerper, LUCA3 antikoerper, Hyl3 antikoerper, hyaluronoglucosaminidase 3 antikoerper, HYAL3 antikoerper, Hyal3 antikoerper

Hintergrund: This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon.

Molekulargewicht: 47 kDa

UniProt: O43820

Pathways: Glycosaminoglycan Metabolic Process