MAGEA10 antikoerper, CT1.10 antikoerper, MAGE10 antikoerper, RGD1563693 antikoerper, MAGEA11 antikoerper, MAGE family member A10 antikoerper, melanoma-associated antigen 10 antikoerper, melanoma antigen family A, 10 antikoerper, putative MAGE domain-containing protein MAGEA13P antikoerper, MAGEA10 antikoerper, LOC509805 antikoerper, Magea10 antikoerper, LOC492173 antikoerper
Hintergrund
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80 % sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants.