1R20 antikoerper, BL34 antikoerper, IER1 antikoerper, IR20 antikoerper, RGS1 antikoerper, 1r20 antikoerper, bl34 antikoerper, ier1 antikoerper, ir20 antikoerper, regulator of G protein signaling 1 antikoerper, regulator of G-protein signaling 1 antikoerper, regulator of G-protein signaling 1 S homeolog antikoerper, Regulator of G-protein signaling 1 antikoerper, RGS1 antikoerper, Rgs1 antikoerper, rgs1.S antikoerper, rgs1 antikoerper
Hintergrund
This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.