GRPR Antikörper
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- Target Alle GRPR Antikörper anzeigen
- GRPR (Gastrin-Releasing Peptide Receptor (GRPR))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GRPR Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Synthetic peptide of human GRPR
- Isotyp
- IgG
- Top Product
- Discover our top product GRPR Primärantikörper
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- Applikationshinweise
- WB 1:200-1:1000, IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.1 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- GRPR (Gastrin-Releasing Peptide Receptor (GRPR))
- Andere Bezeichnung
- GRPR (GRPR Produkte)
- Synonyme
- GRPR antikoerper, GRP-R antikoerper, gastrin releasing peptide receptor antikoerper, GRPR antikoerper, Grpr antikoerper
- Hintergrund
- Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.
- Molekulargewicht
- 43 kDa
- NCBI Accession
- NP_005305
- UniProt
- P30550
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