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SMG8 Antikörper

SMG8 Reaktivität: Human, Maus IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7238174
  • Target Alle SMG8 Antikörper anzeigen
    SMG8 (Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
    Reaktivität
    • 13
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 13
    Kaninchen
    Klonalität
    • 13
    Polyklonal
    Konjugat
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SMG8 Antikörper ist unkonjugiert
    Applikation
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Synthetic peptide of human SMG8
    Isotyp
    IgG
  • Applikationshinweise
    IHC 1:25-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.3 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SMG8 (Smg-8 Homolog, Nonsense Mediated mRNA Decay Factor (SMG8))
    Andere Bezeichnung
    SMG8 (SMG8 Produkte)
    Synonyme
    C17orf71 antikoerper, 1200011M11Rik antikoerper, C19H17orf71 antikoerper, SMG8, nonsense mediated mRNA decay factor antikoerper, smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans) antikoerper, Protein smg-8 antikoerper, SMG8 antikoerper, Smg8 antikoerper, smg-8 antikoerper
    Hintergrund
    Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity.
    NCBI Accession
    NP_060619
    UniProt
    Q8ND04
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