ACSVL5 antikoerper, FATP antikoerper, FATP1 antikoerper, Fatp antikoerper, FATP-1 antikoerper, FATP-1c antikoerper, solute carrier family 27 member 1 antikoerper, solute carrier family 27 (fatty acid transporter), member 1 antikoerper, SLC27A1 antikoerper, Slc27a1 antikoerper
Hintergrund
The protein involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids .Highest levels of expression are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver.