NOD2 Antikörper

Produktnummer ABIN7238735

Produktdetails anti-NOD2 Antikörper

Target: NOD2 (Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOD2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human NOD2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.8 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NOD2

Target: NOD2 (Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2))

Andere Bezeichnung: NOD2 (NOD2 Produkte)

Synonyme: ACUG antikoerper, BLAU antikoerper, CARD15 antikoerper, CD antikoerper, CLR16.3 antikoerper, IBD1 antikoerper, NLRC2 antikoerper, NOD2B antikoerper, PSORAS1 antikoerper, Card15 antikoerper, F830032C23Rik antikoerper, Nlrc2 antikoerper, caspase recruitment domain 15 protein antikoerper, nucleotide binding oligomerization domain containing 2 antikoerper, nucleotide-binding oligomerization domain containing 2 antikoerper, TTHERM_01951320 antikoerper, NOD2 antikoerper, Nod2 antikoerper

Hintergrund: This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome.

NCBI Accession: NP_071445

UniProt: Q9HC29

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome