CDK11 Antikörper

Produktnummer ABIN7238792

Produktdetails anti-CDK11 Antikörper

Target: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human CDK11A/CDK11B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CDK11

Target: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Andere Bezeichnung: CDK11B (CDK11B Produkte)

Hintergrund: Cyclin-dependent kinases (CDKs)are a family ofproteinkinasesfirst discovered for their role in regulating thecell cycle. They are also involved in regulatingtranscription, mRNA processing, and the differentiation of nerve cells. They are present in all knowneukaryotes, and their regulatory function in thecell cyclehas been evolutionarily conserved. CDKs are relatively small proteins, witHuman, Mouseolecular weights ranging from 34 to 40 kDa, and contain little more than the kinase domain. By definition, a CDK binds a regulatory protein called a cyclin. Without cyclin, CDK has little kinase activity, only the cyclin-CDK complex is an active kinase. CDKs phosphorylate their substrates on serines and threonines, so they are serine-threonine kinases.

Molekulargewicht: 93 kDa

NCBI Accession: NP_277021

UniProt: B7ZVY7

Pathways: Regulation of Lipid Metabolism by PPARalpha, M Phase