CDK12 Antikörper

Produktnummer ABIN7001259

Produktdetails anti-CDK12 Antikörper

Target: CDK12 (CRKRS) (Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK12 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human CDK12

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:25-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CDK12

Target: CDK12 (CRKRS) (Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS))

Andere Bezeichnung: CDK12 (CRKRS Produkte)

Synonyme: AC017581 antikoerper, CG7597 antikoerper, Dmel\\CG7597 antikoerper, anon-WO0140519.165 antikoerper, cg7597 antikoerper, dCDK12 antikoerper, gi24668141 antikoerper, CRK7 antikoerper, CRKR antikoerper, CRKRS antikoerper, hCDK12 antikoerper, 1810022J16Rik antikoerper, AI646528 antikoerper, Crk7 antikoerper, Crkrs antikoerper, D11Ertd752e antikoerper, Pksc antikoerper, Cyclin-dependent kinase 12 antikoerper, cyclin dependent kinase 12 antikoerper, cyclin-dependent kinase 12 antikoerper, Cdk12 antikoerper, CDK12 antikoerper

Hintergrund: CrkRS (Cdc2-related kinase, arginine/serine-rich, also designated CRK7 and CRKR) is an ubiquitous protein that appears to localize to the nucleus and link transcription and splicing machinery. CrkRS belongs to the serine/threonine protein kinase family and Cdc2/Cdkx subfamily. CrkRS has extensive proline-rich regions that resemble SH3 and WW domain binding sites, and an RS domain that is characteristic of splicing factors. The protein kinase domain of CrkRS is 89 % identical to the CHED protein kinase, also designated CDC2L5 and cell division cycle 2-like 5 (cholinesterase-related cell division controller), however outside the kinase domains the two proteins are unique. Cell cycle control kinases can phosphorylate proteins important for differentiation and apoptosis and provide connections between proliferation, differentiation, apoptosis, and neurocytoskeleton dynamics.

NCBI Accession: NP_057591

UniProt: Q9NYV4