Desmocollin 2 Antikörper

Produktnummer ABIN7238891

Produktdetails anti-Desmocollin 2 Antikörper

Target: Desmocollin 2 (DSC2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Desmocollin 2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human DSC2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.7 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Desmocollin 2

Target: Desmocollin 2 (DSC2)

Andere Bezeichnung: DSC2 (DSC2 Produkte)

Synonyme: ARVD11 antikoerper, CDHF2 antikoerper, DG2 antikoerper, DGII/III antikoerper, DSC3 antikoerper, AW228162 antikoerper, Dsc2a antikoerper, Dsc2b antikoerper, DSC2 antikoerper, desmocollin 2 antikoerper, DSC2 antikoerper, Dsc2 antikoerper

Hintergrund: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11.

NCBI Accession: NP_077740

UniProt: Q02487