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HMGCS1 Antikörper

HMGCS1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7239032
  • Target Alle HMGCS1 Antikörper anzeigen
    HMGCS1 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1))
    Reaktivität
    • 41
    • 35
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 59
    • 4
    • 1
    Kaninchen
    Klonalität
    • 63
    • 1
    Polyklonal
    Konjugat
    • 31
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HMGCS1 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 21
    • 13
    • 13
    • 11
    • 9
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Synthetic peptide of human HMGCS1
    Isotyp
    IgG
    Top Product
    Discover our top product HMGCS1 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.4 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    HMGCS1 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 1 (Soluble) (HMGCS1))
    Andere Bezeichnung
    HMGCS1 (HMGCS1 Produkte)
    Synonyme
    HMGCS antikoerper, zgc:56481 antikoerper, B130032C06Rik antikoerper, 3-hydroxy-3-methylglutaryl-CoA synthase 1 antikoerper, 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) antikoerper, 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 antikoerper, 3-hydroxy-3-methylglutaryl coenzyme A synthase antikoerper, hydroxymethylglutaryl-CoA synthase antikoerper, 3-hydroxy-3-methylglutaryl-CoA synthase antikoerper, hydroxymethylglutaryl coenzyme A synthase antikoerper, 3-hydroxy-3-methylglutaryl-CoA synthase 1 S homeolog antikoerper, HMGCS1 antikoerper, hmgcs1 antikoerper, Hmgcs1 antikoerper, mvaS antikoerper, SAS2432 antikoerper, SZO_RS04705 antikoerper, SEQ_1109 antikoerper, NAEGRDRAFT_77778 antikoerper, hmgcs1.S antikoerper
    Hintergrund
    HMG-CoA Synthase exists as both a mitochondrial (mHMGCS) and cytoplasmic (cHMGCS) enzyme that condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA. The HMG-CoA produced by cHMGCS is transformed into mevalonate by HMG-CoA reductase, which starts isoprenoid biosynthesis. End products of the isoprenoid pathway include cholesterol, ubiquinone, dolichol, isopentenyl adenosine and farnesyl groups. mHMGCS, together with HMG-CoA Lyase, is responsible for ketone body biosynthesis. mHMGCS is expressed in liver and kidney. Fasting, cAMP and fatty acids increase the level of transcription of mHMGCS, while feeding and insulin repress it. A regulatory element within the mHMGCS promoter confers transcriptional regulation by PPAR, RXR, COUP-TF and HNF-4.
    Molekulargewicht
    57 kDa
    NCBI Accession
    NP_001091742
    UniProt
    Q01581
    Pathways
    Regulation of Lipid Metabolism by PPARalpha
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